No issues whatsoever by manually upgrading by means of istioctl and redeploying affected workloads resp. pods in the K3s Kubernetes cluster.
Istio 1.16.1
Announcing Istio 1.16.1
No problems automatically updating the Docker image, migrating the application manually and run the container by Watchtower with dependency update facilitated by Mend's Renovate Bot. This MR contains the following updates: Package Update Change docker.io/matomo minor 5.3.2 -> 5.4.0 Release Notes
No problems upgrading the backend Docker container with a Docker compose yaml file within Portainer and by means of Portainer DevOps resp. GitOps with dependency update facilitated by Mend's Renovate Bot. This MR contains the following updates: Package Update Change docker.io/dependencytrack/apiserver (source, changelog) patch 4.
No problems automatically updating the monolithic Docker image and run the container by Watchtower with dependency update facilitated by Mend's Renovate Bot. This MR contains the following updates: Package Update Change docker.io/gitlab/gitlab-ce (changelog) patch 18.3.0-ce.0 -> 18.3.1-ce.0
Manual patch upgrade and OS update without node reboot without any issues only on intel architecture. This MR contains the following updates: Package Update Change k3s (source, changelog) patch v1.33.3+k3s1 -> v1.33.4+k3s1